Podcast
The a16z Show
Andreessen Horowitz
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
— All episodes
EPISODES
- 01
Oct 9, 2026 · 54m E1223
Chips, Memory, and Power | Pat Gelsinger
a16z's Raghu Raghuram and Guido Appenzeller sit down with Playground Global General Partner and former Intel CEO Pat Gelsinger to discuss the next wave of se...
- 02
Oct 8, 2026 · 56m E1222
Building the Cloud for an Agentic World | AWS CEO Matt Garman
a16z’s Raghu Raghuram sits down with AWS CEO Matt Garman to discuss how AI is reshaping the cloud, from the needs of AI-native startups to infrastructure inc...
- 03
Oct 7, 2026 · 40m E1221
How Valon Rebuilt a $13 Trillion Industry From Scratch
a16z General Partner Angela Strange sits down with Valon’s Andrew Wang and Linda Du to unpack what it takes to rebuild the infrastructure underneath a $13 tr...
- 04
Oct 6, 2026 · 49m E1220
Building Defense for the Agentic Era: Kevin Mandia
a16z General Partner David George sits down with Armadin founder and CEO Kevin Mandia to discuss what happens to cybersecurity when attackers can operate at...
- 05
Oct 5, 2026 · 51m E1219
The Top 100 Consumer AI Apps: Who’s Actually Paying?
a16z Editorial Partner Elena Burger sits down with investing partners Olivia Moore and Josh Elman to unpack the seventh edition of a16z’s Top 100 Consumer AI...
- 06
Oct 4, 2026 · 55m E1218
David George & Jack Altman on AI, Autonomy, and the Next $25 Trillion
a16z General Partner David George joins Jack Altman on Uncapped to make the case that many of the biggest debates in AI are framed the wrong way. Frontier mo...
- 07
Oct 3, 2026 · 48m E1217
Beyond the God Model | Alex Atallah & Amjad Masad
A16z’s Erik Torenberg sits down with OpenRouter’s Alex Atallah and Replit founder and CEO Amjad Masad to discuss why the future of AI may look less like one...
- 08
Oct 2, 2026 · 59m E1216
Why AI Agents Can Beat the Incumbents
a16z’s Seema Amble and Elena Burger sit down with Lio co-founder and CEO Vladimir Keil to ask where AI-native startups have an advantage when incumbent softw...
- 09
Oct 1, 2026 · 45m E1215
Rebuilding the Internet for Privacy | Barrett Lyon on DoxxNet
a16z’s Joel de la Garza sits down with DoxxNet founder Barrett Lyon to discuss what it would take to rebuild the internet around privacy, direct communicatio...
- 10
Sep 30, 2026 · 53m E1214
The $1 Trillion AI Buildout | State of Markets
a16z’s David George, Sarah Wang, Alex Immerman, and Santiago Rodriguez unpack 25 key charts from the latest State of Markets presentation, from the scale of...
- 11
Sep 29, 2026 · 51m E1213
The Personal Agent Race Is Here | Anish Acharya & David Pawlan
a16z General Partner Anish Acharya sits down with Assistant Benchmark creator David Pawlan to unpack the sudden explosion of personal AI agents and what it w...
- 12
Sep 28, 2026 · 43m E1212
AI Can Write Code. Why Isn’t Software Better?
a16z’s Ben Horowitz and Martin Casado sit down with TypeSafe AI founder Diogo Almeida to ask a simple question: AI has become remarkably capable, so where is...
- 13
Sep 27, 2026 · 48m E1211
Building a Team at AI Speed | Harvey’s Maggie Landers
a16z’s Katie Kirsch sits down with Harvey VP of Talent Maggie Landers to discuss what happens inside a company growing at AI speed, and how you preserve cult...
- 14
Sep 26, 2026 · 56m E1210
Aaron Levie, Steven Sinofsky & Martin Casado: How Do You Secure a World of AI Agents?
Erik Torenberg sits down with Box CEO Aaron Levie, and a16z’s Martin Casado, and Steven Sinofsky to debate how the AI industry should think about safety, sec...
- 15
Sep 25, 2026 · 50m E1208
The Reputation Graph of Silicon Valley | Introducing Cosign
a16z’s Erik Torenberg sits down with Josh Elman, Olivia Moore, and David Booth to introduce Cosign, a new product built around professional reputation and th...
- 16
Sep 24, 2026 · 27m E1209
The Case Against an AI Pause | Eddy Lazzarin
a16z crypto General Partner Eddy Lazzarin joins Theo Jaffee on MTS to debate the increasingly prominent calls to slow AI development and whether the current...
- 17
Sep 23, 2026 · 47m E1207
Amjad Masad on Rethinking College for the AI Era
Erik Torenberg sits down with Replit founder and CEO Amjad Masad and Horowitz and Andreessen Academy co-founder and CEO Gagan Biyani to ask what education sh...
- 18
Sep 22, 2026 · 43m E1206
Why a16z is Building a New School for the AI Era | Ben Horowitz
Ben Horowitz and Erik Torenberg sit down with Gagan Biyani to introduce the Horowitz and Andreessen Academy and discuss a bigger question: what should educat...
- 19
Sep 21, 2026 · 29m E1205
AI Safety Language Is Destroying the Debate | Steven Sinofsky
a16z Board Partner and former Microsoft Windows president Steven Sinofsky joins Theo Jaffee and Sofia Puccini on MTS to argue that the language we use to des...
- 20
Sep 20, 2026 · 57m E1204
Nas, Grandmaster Caz, Steve Stoute & Ben Horowitz on Paying Hip-Hop’s Pioneers Their Due
Ben Horowitz and Erik Torenberg sit down with Nas, Grandmaster Caz, and Steve Stoute for a conversation about the Paid in Full Foundation and its mission to...
- 21
Sep 19, 2026 · 1h E1203
What Makes a Consumer AI Product Stick? | Josh Elman
a16z Partner Josh Elman joins Ollie Forsyth on New Economies to discuss the next wave of consumer AI and what separates a product people try once from one th...
- 22
Sep 18, 2026 · 1h 8m E1202
Databricks CEO on AI Pacing, Cyber Risk, and the Enterprise
Databricks co-founder and CEO Ali Ghodsi joins a16z General Partners Martin Casado and Sarah Wang for a conversation about AI risk, recursive self-improvemen...
- 23
Sep 17, 2026 · 39m E1201
The Next Frontier of AI Video Is Control
a16z General Partner Jennifer Li sits down with fal co-founder Gorkem Yurtseven and Head of Engineering Batuhan Taskaya to discuss what changes when generati...
- 24
Sep 16, 2026 · 52m E1200
The AI-Native CRM
a16z’s Alex Rampell and Joe Schmidt sit down with Lightfield co-founder and CEO Keith Peiris to discuss what it takes to rethink the CRM for an AI-native wor...
- 25
Sep 15, 2026 · 42m E1199
The Age of Body Futurism | Ruby Justice Thelot
Elena Burger sits down with academic and cyber ethnographer Ruby Justice Thelot to explore the increasingly blurry line between internet culture and the real...
- 26
Sep 14, 2026 · 51m E1198
Greg Brockman on Why OpenAI Says We’re Entering the AGI Era
Ben Horowitz and Erik Torenberg sit down with OpenAI co-founder and President Greg Brockman to discuss why he believes AI has entered a new phase, what OpenA...
- 27
Sep 13, 2026 · 23m E1197
World Models, Robotics, and the Future of 3D AI
World Labs co-founder Justin Johnson joins MTS hosts Theo Jaffee and Sofia Puccini to discuss Atlas, World Labs’ latest world model, and the broader case for...
- 28
Sep 12, 2026 · 1h 18m E1196
Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast
a16z General Partner Anish Acharya joins Lenny Rachitsky on Lenny’s Podcast to discuss why fears of an AI-driven “permanent underclass” may be misplaced, how...
- 29
Sep 11, 2026 · 38m E1195
What It Takes to Build a Startup | Andrew Chen & Matt Perault
a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks lik...
- 30
Sep 10, 2026 · 49m E1194
How AI Is Rewriting the Power Law of Venture Capital
a16z’s Jen Kha and David George sit down with Accolade Partners’ Aram Verdiyan to discuss how AI is changing the power law of technology investing, why the l...
- 31
Sep 9, 2026 · 39m E1193
Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan
a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Rayan Krishnan to discuss one of AI’s increasingly difficult problems...
- 32
Sep 8, 2026 · 1h 5m E1192
OpenAI Researchers on the Future of Mathematical Reasoning
a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are ad...
- 33
Sep 7, 2026 · 8m E1191
Can Open Source Keep AI Power From Concentrating?
MTS host Sophia Dew visits the Open Source AI Summit in San Francisco to ask researchers and founders across the AI stack a central question: can open source...
- 34
Sep 6, 2026 · 28m E1190
Your AI Doctor Is Coming | Julie Yoo
a16z General Partner Julie Yoo joins MTS host Sophia Dew to explain why she believes healthcare could benefit more from AI than almost any other industry, an...
- 35
Sep 5, 2026 · 31m E1189
Aaron Levie on Why Open AI Wins
Box co-founder and CEO Aaron Levie joins MTS hosts Theo Jaffee and Sofia Puccini to make the case for open-weight AI, unpack the economics of open versus clo...
- 36
Sep 4, 2026 · 44m E1188
Fei Fei Li: The Race to Build World Models For AI
World Labs co-founders Fei-Fei Li, Justin Johnson, and Ben Mildenhall join a16z General Partner Martin Casado to discuss Atlas, their latest world model, and...
- 37
Sep 3, 2026 · 1h E1187
The $100B Niches Hiding Inside Payments
Erik Torenberg is joined by a16z General Partner Alex Rampell and Affirm Co-Founder and CEO Max Levchin for a conversation on 25 years of fintech, from the e...
- 38
Sep 2, 2026 · 40m E1186
Inside Moderna’s Personalized Cancer Vaccine
a16z General Partner Jorge Conde sits down with Moderna CEO Stéphane Bancel to discuss a major milestone for mRNA technology: positive Phase 3 results from M...
- 39
Sep 1, 2026 · 1h 3m E1185
Daniel Litt: The Mathematician's Guide to AI
a16z’s Lisha Li sits down with Daniel Litt, Assistant Professor of Mathematics at the University of Toronto, to unpack AI's rapid progress in mathematics, wh...
- 40
Aug 31, 2026 · 1h 15m E1184
Gavin Baker: Why AI Demand Is Outrunning Compute Supply
a16z’s David George sits down with Gavin Baker to unpack the state of the AI boom, why demand for intelligence may still be dramatically underestimated, and...
- 41
Aug 30, 2026 · 24m E1183
Why a16z Launched the Machine Age Fund | Jen Kha
a16z Managing Partner and Head of Global Partnerships Jen Kha joins MTS hosts Theo Jaffee and Sophia Dew to discuss a16z's Machine Age Fund and the investmen...
- 42
Aug 29, 2026 · 34m E1182
Why 1,200 AI Agents Started Working Together | Ryan Greenblatt
Ryan Greenblatt, Chief Scientist at Redwood Research, joins MTS host Theo Jaffee to unpack a new independent investigation into the OpenAI Hugging Face hacki...
- 43
Aug 28, 2026 · 55m E1181
The Infrastructure Behind the Machine Age
Ben Horowitz, Martin Casado, Raghu Raghuram, and Erik Torenberg discuss the launch of a16z's new Machine Age Fund and the infrastructure buildout behind AI,...
- 44
Aug 27, 2026 · 39m E1180
Inside Cursor: The Anatomy of a Generational Startup
a16z General Partners Martin Casado, Sarah Wang, and Matt Bornstein unpack the story of Cursor: how a small, product-obsessed team entered one of the most co...
- 45
Aug 26, 2026 · 37m E1179
The State of AI: Macro, Apps, and Consumer
Anish Acharya joins Jen Kha to break down the next frontier of AI, from the evolving model landscape and open-source AI to why the application layer, and con...
- 46
Aug 25, 2026 · 1h 3m E1178
The New Economics of AI | Martin Casado & Steven Sinofsky
a16z General Partners Martin Casado and Erik Torenberg are joined by Board Partner Steven Sinofsky to explore what recent breakthroughs in AI and mathematics...
- 47
Aug 24, 2026 · 35m E1177
Why Medical AI Needs a Referee | Protege's Engy Ziedan
Daisy Wolf and Eva Steinman are joined by Engy Ziedan, co-founder and Chief Scientific Officer of Protege, to discuss why medical AI has a measurement proble...
- 48
Aug 22, 2026 · 42m E1176
Martin Casado on Where the Value Is Going in AI
Martin Casado joins MTS hosts Theo Jaffee and Sophia Dew to unpack where value is actually accruing in AI, why this technology cycle looks fundamentally diff...
- 49
Aug 21, 2026 · 25m E1175
How Microsoft Is Securing the Agentic Enterprise | Aaron Zollman
a16z's Joel De La Garza is joined by Aaron Zollman, Deputy CISO at Microsoft Gaming, to discuss how security teams can embrace AI agents without losing contr...
- 50
Aug 20, 2026 · 45m E1174
How Global Networks Are Reshaping Startup Success
Elena Burger is joined by a16z’s Angela Strange and Gabriel Vasquez to discuss the rise of the "borderless founder": entrepreneurs who bring the networks and...
- 51
Aug 19, 2026 · 42m E1173
How Whatnot Built a Global Marketplace
a16z General Partner David George is joined by Grant LaFontaine, co-founder of Whatnot, to unpack how a marketplace that started with collectibles evolved in...
- 52
Aug 18, 2026 · 22m E1172
How Do You Defend Against AI That Can Hack?
a16z's Joel De La Garza is joined by Nick Warner of Neo and Max Pollard of Cotool to discuss what happens when cybersecurity tools built to defend against hu...
- 53
Aug 17, 2026 · 54m E1171
Stripe’s AI Strategy: Build More, Not Less
a16z General Partner David George is joined by Will Gaybrick, President of Product & Business at Stripe, to discuss how AI is changing the way Stripe builds...
- 54
Aug 14, 2026 · 33m E1162
Ben Horowitz and Travis Kalanick on Building Again
Ben Horowitz, Travis Kalanick, and Erik Torenberg take the stage at Atoms' launch event for a candid fireside conversation about entrepreneurship, company bu...
- 55
Aug 13, 2026 · 44m E1170
The Two Ways to Sell AI: Lighthouse or Landgrab?
Elena Burger is joined by a16z's Andy McCall and Joe Schmidt to break down two very different ways AI startups can go to market: the lighthouse and the landg...
- 56
Aug 12, 2026 · 52m E1169
Garry Tan on Taste, Agents and Founder Ambition
Anish Acharya is joined by Garry Tan, President and CEO of Y Combinator, for a conversation about how AI is rewriting the startup playbook, why founders shou...
- 57
Aug 11, 2026 · 22m E1168
The CISO Playbook for AI Agents | Datadog
a16z's Joel De La Garza is joined by Emilio Escobar, Chief Information Security Officer at Datadog, to discuss what it takes to secure a company where nearly...
- 58
Aug 10, 2026 · 37m E1167
How Kavak Rebuilt Itself Around AI Agents | Alejandro Maza Ayala
Angela Strange and Gabriel Vasquez are joined by Alejandro Maza Ayala, Chief Product & AI Officer at Kavak, to unpack how the Latin American used-car marketp...
- 59
Aug 7, 2026 · 23m E1166
The Reality of AI-Powered Cyberattacks | Truffle Security & Socket
Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the...
- 60
Aug 6, 2026 · 46m E1165
How Open-Source AI Became Critical Infrastructure
Elena Burger and Matt Bornstein are joined by Simon Mo, co-founder and CEO of Inferact, the open-source inference engine powering many of today's most advanc...
- 61
Aug 5, 2026 · 1h 15m E1164
Three Startups Reinventing Critical Infrastructure
This week, a16z American Dynamism Films premiered three short documentaries highlighting companies tackling some of America's biggest industrial challenges:...
- 62
Aug 4, 2026 · 31m E1163
OpenAI's Joshua Achiam: Did We Already Reach AGI?
Theo Jaffee is joined by Joshua Achiam, Chief Futurist at OpenAI, for a conversation on AI cybersecurity, frontier model capabilities, and why he believes so...
- 63
Aug 2, 2026 · 34m E1161
Ruby Thelot on Internet Culture, AI, and the Future of Taste
Sophia Dew and Sofia Puccini are joined by Ruby Thelot, designer, artist, cyberethnographer, professor at NYU, and founder of 13101401, for a wide-ranging co...
- 64
Aug 1, 2026 · 59m E1160
Marc Andreessen and Chris Dixon: What’s at Stake in Crypto Regulation
Marc Andreessen, Chris Dixon, and Robert Hackett discuss one of the most consequential policy debates facing the crypto industry: the push for comprehensive...
- 65
Jul 31, 2026 · 1h 20m E1159
Decagon’s Playbook for Building Enterprise AI Applications
Sarah Wang and Kimberly Tan are joined by Jesse Zhang and Ashwin Sreenivas, co-founders of Decagon, to discuss the evolution of enterprise AI agents, why the...
- 66
Jul 30, 2026 · 58m E1158
AI for America's Small Businesses | Lassie
Alex Rampell and Olivia Moore speak with Lassie cofounders Steijn Pelle and Frédéric Renken about bringing AI to one of the most overlooked parts of the econ...
- 67
Jul 29, 2026 · 51m E1157
AI Micro Dramas, Generative Media, and the Future of Creativity
Justine Moore, partner at Andreessen Horowitz, joins New Economies to explore the rapid evolution of generative media and why AI-native content is reaching a...
- 68
Jul 28, 2026 · 43m E1156
Fei-Fei Li on Spatial Intelligence and Robotics
Last week, World Labs announced its acquisition of SceniX, bringing together two teams working on one of AI's biggest unsolved problems: how to give machines...
- 69
Jul 27, 2026 · 29m E1155
Steven Sinofsky: AI Doesn't Need New Rules Yet
Steven Sinofsky joins Theo Jaffee and Sofia Puccini for a conversation on AI regulation, open-source models, and what history can teach us about technologica...
- 70
Jul 26, 2026 · 32m E1154
Ben Horowitz: The Fight Over Open Source AI
Ben Horowitz joins Theo Jaffee and Sofia Puccini to discuss one of the biggest debates in AI today: the future of open-source models. They examine the growin...
- 71
Jul 24, 2026 · 23m E1153
Sriram Krishnan on Open Source AI's Biggest Week Yet
Sriram Krishnan joins Theo Jaffee and Sofia Puccini just after concluding his tenure as Senior White House Policy Advisor on AI to discuss one of the biggest...
- 72
Jul 23, 2026 · 45m E1152
Building the Physical AI Stack | Travis Kalanick on TBPN
Travis Kalanick joins TBPN to discuss Atoms, his vision for industrial AI, and why he believes the biggest opportunities in AI lie beyond software. He explai...
- 73
Jul 22, 2026 · 1h 32m E1151
Travis Kalanick Is Back | Building the Future of Industrial AI
Travis Kalanick, Ben Horowitz, and Erik Torenberg reunite to reflect on Uber's early days, the investment that almost happened, and why Kalanick believes the...
- 74
Jul 21, 2026 · 1h 20m E1150
Why Physical AI Is the Next Frontier | Applied Intuition
Applied Intuition has spent the past decade building the software that powers intelligent machines, from passenger vehicles and trucks to defense systems, mi...
- 75
Jul 20, 2026 · 28m E1149
Hugging Face's CEO on Open Source AI, Model Routing, and the Future of Competition
As governments weigh new restrictions on frontier AI models, one question is becoming increasingly important: what role should open source play in the future...
- 76
Jul 17, 2026 · 25m E1148
Amjad Masad on Going Direct, Building Replit, and the Future of Software
Recorded live at the New Media Summit, Erik Torenberg sits down with Replit founder and CEO Amjad Masad to discuss founder-led storytelling, building in publ...
- 77
Jul 16, 2026 · 1h 17m E1147
Replay 2025: David Sacks on AI, Crypto, and America's Technology Future
As part of our summer replay series, we're revisiting one of our most-discussed conversations from the past year. David Sacks joins Marc Andreessen, Ben Horo...
- 78
Jul 15, 2026 · 1h 5m E1146
Can Anyone Catch NVIDIA? | The Future of Chips and Infrastructure
As part of our summer replay series, we're revisiting one of our favorite conversations on the future of AI infrastructure. SemiAnalysis founder Dylan Patel...
- 79
Jul 14, 2026 · 31m E1145
Is AI a Bubble? | Gavin Baker on Data Centers, GPUs, and the AI Economy
As part of our summer replay series, we're revisiting one of the standout conversations from Runtime, a16z's conference on AI infrastructure and the future o...
- 80
Jul 13, 2026 · 37m E1144
Before Blockchains, There Was State Machine Replication
Every blockchain today relies on replication techniques first developed in the 1980s by researchers who weren't thinking about cryptocurrencies at all. In th...